One Year Later

My father will not be a centenarian. May he rest in peace...

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I spent some time last autumn in the Neurology section, with him. All those elderly people trying to still function, battling it out, and the nurses and doctors assisting them in Purgatory, matter-of-factly... My respect for the medical establishment, imperfect as it may be, has increased even more. They have not saved my father, but they did extend his life by a few months...

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A neurologist thought I may suffer from a subclinical case of vasculitis. She had me try "Lyrica", which I could not endure. My pain, at its worst, is not worth the side effects and the zoning out. I tried "Gabaran" as well -- much easier on me: I composed many songs on the one and only pill I tried. I am glad to know there are such powerful painkillers out there, but I hope I will never have to use them consistently.

The neurologist also suspected an incipient diabetic neuropathy. Given my high genetic risk of diabetes, over 40%, I figured my following Dr. Peat's recommendations for almost a year must have been quite unfortunate. Luckily for me, her suggestion to help with this one worked wonders: "Milgamma" (B1 as a benfotiamine and B12). It was literally like growing back a bunch of nervous endings... I had come to accept that my right big toe had left the system for some idiosyncratic reason and I was not too worried (I should have been!) Well, I was overwhelmed to feel it return to me! Regeneration after degeneration, so there is hope!

So... I dropped my sugar consumption to almost zero. Peat was definitely wrong for me on this front!

No more weird numbness for me. That is a winner! And no, I don't miss OJ. I see it now, for myself, as the orange specter of diabetes.

Another huge improvement was the disappearance of the CA-125 marker.  I cannot be sure what brought that about. Except giving up sugar, I did not do any other spectacular diet changes.

One small thing I can think of is that I increased garlic consumption. My body was craving it. If it turns out this new garlic habit got rid of some incipient tumor, hey... The stench is a small price to pay. I also brought a bunch of PUFA back into my life in the form of potato chips -- I have to have them at least once or twice a week, dipped in my garlic salsa...

Thyroid function -- I am still at 25 mcg T4, but with my free T4 bumped up into a mid-range of normalcy (it used to hover to the lowest normal and even under that), with a rather high TSH by US standards (2.6). I think this is a pretty reasonable spot, I am sleeping well, I no longer experience those "hit by a truck" moments... Some days are better than others, energy-wise.  My weight is pretty much the same and nobody guesses my age, so I am alright. Actually, I look much better than I feel and people look confused and rather skeptical when they hear about my troubles.

I stopped measuring all the other hormones, I will let my body deal with them. I experimented with supplementation of most and I didn't like it one bit. Maybe I am oversensitive, or maybe I have a low tolerance -- my 23andme results show me as a slow metabolizer for many substances (including coffee, yet another reason for me to not follow Peat), so perhaps I should stay away from any "bio-hacking" that involves hormones. Nobody knows for sure how they work, anyway, so why be a guinea pig, life is too short even without self-experimentation.

In my search for the perfect seaside, I visited Cyprus and loved the taste of their produce... I hated the pollution, though...

I hope you are all doing well and staying healthy and gorgeous.

Dr. C.I. Parhon: A True Pioneer of Endocrinology

I decided to take a short trip to Romania and visit my father. He is doing great, no health issues whatsoever -- I am so proud of him!

I wanted to take advantage of being in Bucharest to check in with the endocrinologist who diagnosed my Hashimoto's last year, maybe discuss my current treatment options with her, but she was on a maternal leave.

As I was trying to find a good alternative, I made a fabulous discovery: there is an entire hospital attached to an institute devoted to endocrinology in Bucharest! The National Institute of Endocrinology was founded in 1946 by Dr. Constantin I. Parhon, who wrote, with Moise Goldstein, the very first treaty of endocrinology, over 800 pages, published in French, in 1909!

There are 42 medical doctors specializing in endocrinology working at the hospital which can host 400 patients. There is a research facility as well, which just got 10 million euros in funding, so things look quite promising... Maybe Dr. Ray Peat should be invited to test some of his theories?

The incredible Dr. Parhon also became the first president of Romania, when the King was forced to abdicate! How about THAT?

Dr. Parhon's fabulous accomplishments include founding yet another hospital, dedicated to old people this time, the first Geriatrics Hospital in the world -- as Parhon considered old age more of a disease than a natural state.

Parhon appointed a woman as director of this Institute of Gerontology and Geriatrics, presumably a former student and follower of his, Dr. Ana Aslan.   She went on to develop a line of youth promoting products that attracted quite a following (A. Onassis, J. Kennedy were among her clients). I think I will try to get a hold of these patented products, "the first medicine designed to delay human aging processes".  And I am in the process of locating a copy of Dr. Parhon's book "Old Age and Its Treatment".

I almost feel grateful to my Hashimoto's for enlarging my horizon... Um... Not really.

I figured there must be some pretty impressive endocrinologists in Bucharest, with such an outstanding school behind them, so I pursued my research.

I scheduled an appointment with none other than the Head of the Romanian Society of Endocrinology, Dr. Mihai Coculescu, whose impressive list of publications on PubMed and whose views on thyroid and estrogen went straight to my heart.  I'm thinking I should bring him Dr. Peat's books, maybe something develops... It would be worthwhile to see Dr. Peat invited to one of these mainstream congresses of endocrinologists. Anyway, the RSE publishes Acta Endocrinologica since...1938. It also publishes "The Romanian Journal of Diabetes, Nutrition and Metabolic Diseases".

I bought for five dollars, from the selection of a street vendor in Bucharest, "Clinical Endocrinology", published in 1976, authored by two of Parhon's collaborators, Stefan Milcu and Marcela Pitis, to which Dr. Coculescu, back then a young research assistant, is listed as a top contributor.

Here is Dr. Coculescu, delivering a speech at the Romanian Academy (in Romanian):

He talks about another illustrious Romanian endocrinologist I knew nothing about, Dr. Paulescu, who first discovered insulin, in 1921.  Dr. Paulescu is a controversial figure because of his antisemitic views.  Many claim that he was robbed of his Nobel prize.

Dr. Parhon is not much talked about in Romania nowadays because he was a communist. I guess Dr. Parhon was either inspired, or a student of Dr. Paulescu's. As Dr. Parhon was openly opposing antisemitism, his relationship with Paulescu must have been at least strained. Fascinating...

Back to 2013: confident that Romania boasts a mighty tradition of endocrinology, I crowned my stay in sunny Bucharest with another doctor's visit and a panel of brand new blood tests, of which I might soon write.